If you’re taking Fish Oil… Your Arteries are Quickly Changing.

A high-level overview of atherosclerosis and why soft (non-calcified) plaque is much more dangerous than stable or calcified plaque due to its susceptibility to rupture and blockage of blood vessels.

Analysis of data using CT angiography, showing that omega-3 supplementation is associated with shifting plaque toward a more stable, fibrous, and calcified profile compared to non-supplementers.

Discussion of randomized control trials suggesting that omega-3s are incorporated into plaque and reduce the presence of macrophages, which are immune cells that normally exacerbate inflammation and instability within the arterial wall.

Summarizing the evidence that while more long-term studies are needed, current findings suggest omega-3s improve cardiovascular health by helping to remodel plaque, making it less inflamed and more stable.