The Link Reaction Explained (Aerobic Respiration)

The pyruvate molecules produced during glycolysis are further oxidized and broken down within the mitochondrion to release the energy stored in the original glucose molecule.

Inside the mitochondrion, pyruvate is oxidized, transferring electrons and hydrogens to NAD+ to form NADH, a vital electron carrier. This process also releases carbon dioxide (CO2); specifically, two of the six CO2 molecules produced during cell respiration are released at this stage and are ultimately exhaled.

The NADH formed will be utilized in the electron transport chain, which is the primary source of ATP. The remaining molecule, acetyl-CoA, will be fed into the Krebs cycle, the next stage of cellular respiration.

This reaction is called the 'link reaction' because it connects glycolysis to the Krebs cycle, allowing the continuous process of aerobic respiration.

For those completing the respiration activity at Bioman Biology, it is recommended to return and complete tasks related to the link reaction. A link to the interactive activity is provided in the video description. Viewers are encouraged to like, subscribe, and explore other free educational resources on Bioman Biology.