Summary
Highlights
Introduction to Vitamin B3 and Glaucoma00:00:00
New research suggests vitamin B3 could protect against glaucoma-related blindness. Dr. Tai introduces the potential of vitamin B3 (niacin) in glaucoma treatment.
What is Vitamin B3?00:00:33
Vitamin B3, or niacin, is a water-soluble B vitamin found in various forms like nicotinic acid and nicotinamide. It's naturally present in foods and available as a supplement. Nicotinamide is found in foods like fish, eggs, cereals, poultry, and nuts.
How Vitamin B3 Benefits Glaucoma00:01:08
Glaucoma affects mitochondria in retinal ganglion cells,impairing their function. Vitamin B3 supports mitochondrial function, helping cells stay healthier and preventing vision loss by converting into nicotinamide adenine dinucleotide (NAD).
Study Results00:02:28
A 2019 study showed glaucoma patients had lower nicotinamide levels. A 2021 study found vitamin B3 and pyruvate supplements improved visual field results in glaucoma patients, potentially by rescuing injured but not dead optic nerve cells.
Ongoing Research and Considerations00:03:44
Several larger, long-term trials are ongoing to determine the long-term benefits of nicotinamide for glaucoma. Consult an ophthalmologist before taking vitamin B3. High doses carry risks like low blood pressure, insulin resistance, liver damage, and macular edema.
Dietary Intake and Other Recommendations00:05:04
No adverse effects have been reported from naturally occurring niacin in foods. Increase vitamin B3 intake through diet (fish, nuts, poultry). Regular exercise helps maintain mitochondrial health.
Important Reminder00:05:36
Vitamin B3 supplementation will be an adjunct to, not a replacement for, glaucoma treatments prescribed by your eye doctor.