Summary
Highlights
Vitamin B1 deficiency commonly manifests as brain fog, fatigue, and digestive issues like constipation and bloating due to impaired vagus nerve function. It can also mimic conditions such as fibromyalgia, chronic fatigue, gastroparesis, heart failure, and neuropathy.
Several lifestyle factors increase the risk of deficiency, including regular alcohol consumption, high-carbohydrate or high-sugar diets, heavy coffee and tea consumption, and inflammatory bowel diseases like Celiac or Crohn's. Gastric bypass surgeries are also significantly linked to metabolic Vitamin B1 depletion.
Multiple classes of common medications can lead to or aggravate deficiency, including diuretics, proton pump inhibitors, H2 blockers, certain antibiotics, chemotherapy, and metformin. Patients taking these drugs should monitor their B1 levels as symptoms of deficiency are often misidentified as progression of the underlying condition being treated.
The speaker advises consulting with a nutritionally-focused healthcare provider and recommends using an Intracellular Nutrient Analysis (INA) test to accurately measure Vitamin B1 status rather than assuming common lab ranges reflect individual functional needs.