PHARMA D1P1

Drug Absorption Factors00:00:17

Discusses factors affecting drug absorption including drug form, route of administration (IV, IM, SubQ, Intradermal), blood flow to the site of administration, GI function, and the impact of stomach contents (empty stomach vs. with food) on absorption rates.

Drug Distribution and Metabolism00:14:29

Explains how drugs are transported in the body via capillaries and the significance of protein binding. It details the blood-brain barrier's impact on CNS drugs and the liver's role in metabolism and biotransformation.

Drug Excretion and Pharmacodynamics00:22:13

Covers elimination primarily through the kidneys, the risks of drug retention, and the science of pharmacodynamics—how drugs interact with living systems—including factors like age, weight, and environmental conditions.

Drugs Affecting the Nervous System00:37:45

Examines autonomic nervous system drugs, specifically cholinergic versus adrenergic agents, their respective mimetics and lytics, and clinical applications for conditions like glaucoma and heart block.

Analgesics and Narcotics00:50:39

Details narcotic agonists and antagonists, focusing on opioids like morphine and fentanyl. It emphasizes nursing considerations such as monitoring respiratory rates, vital signs, and safety protocols for potential sedation or toxicity.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)01:12:12

Discusses NSAIDs like ibuprofen, aspirin, and naproxen, highlighting their anti-inflammatory, analgesic, and antipyretic properties. It addresses common side effects like GI irritation and bleeding, and the importance of proper administration to protect the gastric lining.